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Avoid high doses in pregnancy (max of 2000mg/day). Commission E suggests people with gallstones consult their physician before use. Use with caution in gastric ulcers or reflux. Suspend high dose use (>10g) 1 week before surgery.
Known drug interactions:
Avoid with warfarin (Coumadin, Marevan). May increase prothrombin time and international normalised ratio (INR) values. Patients should be monitored for prothrombin & INR values.
Use with caution:
Antiplatelet medications including Aspirin (including Aspro, Solprin, Astrix, Cartia). Co-prescription may increase bruising & bleeding.